As Anakin and Obi-Wan load a cuffed Dr. Vindi into a shuttle bound for Theed, the scientist's assistant droid makes off with one last vial of the virus, successfully detonating it in the underground lab.

Emergency bulkheads begin slamming shut. Captain Rex and his clones race to make it to a safe room, but it seems too late. Ahsoka uses the Force to hold the doors open long enough for the clones and her to jump through.

Elsewhere, Padmé and Jar Jar are secure in another safe room and within their hazard suits. Padmé is determined to stop any remaining battle droids from leaving the lab, which would release the virus into the open.

In Ahsoka's safe room, the clones discover that some of the virus made it past the sealing doors. They have all been exposed to the contaminant. Rex is still determined to stop any droids from leaving the compound, even if it's the last thing he does.

Back at Theed, Captain Typho has been researching the first outbreak of Blue Shadow Virus and has found a possible antidote in the historical archive: a little known extract made from reeksa root, a vine found only on Iego, world of a thousand moons. Anakin and Obi-Wan will venture into Separatist-controlled space to retrieve the root.

The Twilight arrives at Iego. It weaves its way through a dense debris field surrounding the planet before landing at the spaceport city of Cliffhold amid the basaltic spires of Iego's spaceport. A strange collection of battle droids greet the Twilight. Anakin impulsively charges into the horde and cuts down several before he realizes they are no threat.

The droids have been reprogrammed by Jaybo Hood, a 10-year old kid who commandeered a warehouse full of inactive droids left behind by the Separatists.

Jaybo instructs Anakin and Obi-Wan to climb down to the lower canyon floors to find the root. There, Skywalker pulls a spade from his backpack and begins digging for a root. The reeksa vines start writhing, revealing themselves to be enormous, ravenous carnivorous plants with sharpened spikes for teeth and deadly thorns along their length. The plants begin snapping at the Jedi, but Anakin secures the root quickly enough for them to retreat back to the cliff-face.

With the root in hand, the Jedi board the Twilight and fly the spice freighter up into the debris field. Suddenly, laser beams begin lancing forth from some of the rocks, forming a web of deadly energy. Kenobi surmises that the Separatists must have installed the laser field to keep anyone from leaving Iego.

Obi-Wan recruits Jaybo to donate a number of remote-controlled vulture droids in a bid to escape the laser web. R2-D2 will control the vulture droids as a distraction for the laser field, while the Twilight targets the web's primary node.

On Naboo, Padmé does what she can to alleviate the suffering of the infected clones. Ahsoka collapses, overcome by the virus.

The Jedi execute their plan. As the Twilight opens fire on the primary node, a chain reaction erupts as the laser web unbalances and emitters overload, sparking a series of explosions which cause the web to collapse. With no time to waste, the Twilight leaps into hyperspace, en route to Naboo.

On Naboo, Anakin and Obi-Wan take a gunship into the eastern swamps, where medical droids are tending to the infected. The virus has been neutralized, and those afflicted -- including Padmé, Ahsoka and Rex -- will make a full recovery.